OECD TG 405: Scientific and Ethical Approach to the Assessment of Acute Eye Irritation and CorrosionThe eye is one of the body’s...
In vitro cell culture unit –
“In vitro biological evaluation using validated mammalian cell lines for cytotoxicity, irritation and sensitisation endpoints, performed under GLP and ISO 10993-5 / -10 / -23 frameworks, supporting 3R-aligned regulatory submissions.”
Tests performed:
- (MTT / NRU / XTT, direct contact, agar overlay) – ISO 10993-5:2009
- OECD TG 439; ISO 10993-23:2021
- OECD TG 431 / 430
- OECD TG 437 / 438 / 492
- OECD TG 442C / 442D / 442E (DA, KeratinoSens™, h-CLAT)
Two Key Guidelines for the Assessment of Skin Irritation: OECD TG 404 and ISO 10993-23:2021 In the biocompatibility assessment of...
From Repeated-Dose Toxicity to Carcinogenicity: Long-Term Safety Assessment Using OECD Test Guidelines 407, 408, 452, and 453 Und...