What Is a Skin Irritation/Corrosion Test?

Skin irritation and corrosion tests are important toxicological studies conducted to evaluate the irritant or corrosive effects a substance may cause upon contact with the skin. These tests play a critical role in safety assessments of chemical substances, biocidal products, cosmetic raw materials, medical devices, pharmaceuticals, and industrial products.

At NanoTox, we provide internationally recognized toxicity testing services using infrastructure compliant with GLP (Good Laboratory Practice) standards.

Purpose of the Skin Irritation/Corrosion Test

Skin Irritation/Corrosion studies aim to determine the reversible irritation or irreversible tissue damage that the tested substance may cause upon contact with the skin.

Through these studies:

• Product safety assessments,
• Chemical classification processes,
• Labeling requirements,
• Regulatory and licensing applications,
• Human health risk assessments

are supported by the necessary scientific data.

Studies in Compliance with OECD Guidelines

Skin Irritation / Corrosion tests conducted at NanoTox are performed in accordance with internationally recognized OECD test guidelines. The primary methods used include:

• OECD 404 – Acute Dermal Irritation / Corrosion
• OECD 430 – In Vitro Skin Corrosion
• OECD 431 – In Vitro Skin Corrosion: Reconstructed Human Epidermis Test Method
• OECD 439 – In Vitro Skin Irritation

are included.

Studies conducted in accordance with these guidelines ensure the attainment of reliable results accepted by global authorities.

GLP-Compliant Testing Services

Studies conducted in accordance with GLP principles ensure quality assurance throughout the planning, implementation, monitoring, recording, reporting, and archiving processes.

As NanoTox:

• Our modern laboratory infrastructure,
• Our experienced team of experts,
• Our work processes compliant with international standards,
• Our science- and quality-focused approach

enable us to deliver reliable and reproducible results.

Parameters Evaluated in Skin Irritation/Corrosion Studies

Various dermatological and toxicological parameters are evaluated in detail throughout the test. These include:

• Erythema formation,
• Edema assessment,
• Tissue damage observations,
• Corrosive effect assessments,
• Irritation severity,
• Histopathological examinations

are included.

Thanks to these comprehensive evaluations, the potential effects of the tested product on the skin are analyzed in detail.

Reliable Toxicity Studies with NanoTox

NanoTox conducts Skin Irritation/Corrosion studies in accordance with international quality standards as part of its GLP-compliant toxicity testing services. We offer professional solutions to reliably obtain the scientific data required for product safety and regulatory processes.

For detailed information about Skin Irritation/Corrosion tests and our other toxicology services, please contact NanoTox.