OECD TG 442C / 442D / 442E: Field Experience with 2o3 DA and In Vitro Alternatives in Skin Sensitization Skin sensitization asses...
In vitro cell culture unit
In vitro biological evaluation using validated mammalian cell lines for cytotoxicity, irritation and sensitisation endpoints, performed under GLP and ISO 10993-5 / -10 / -23 frameworks, supporting 3R-aligned regulatory submissions.
Tests performed:
- (MTT / NRU / XTT, direct contact, agar overlay) – ISO 10993-5:2009
- OECD TG 439; ISO 10993-23:2021
- OECD TG 431 / 430
- OECD TG 437 / 438 / 492
- OECD TG 442C / 442D / 442E (DA, KeratinoSens™, h-CLAT)
OECD TG 437 / 438 / 492: Comparative Analysis of In Vitro Alternatives for Eye Irritation The assessment of eye irritation and co...
Determination of Skin Corrosion Using In Vitro MethodsThe most serious local toxic effect that can result from skin contact with c...
